PRE-MARKET | November 30, 2016 | #OPEC, $CL_F, $SCO, $USO, $ES_F, $TLT, $AMZN, $SPLK, $GE, $GPRO

PRE-MARKET | November 30, 2016 | #OPEC, $CL_F, $SCO, $USO, $ES_F, $TLT, $AMZN, $SPLK, $GE, $GPRO

PRE-MARKET MOVERS

 

UPGRADES

1. ABUS:$ABUS upgraded to Buy from Neutral at Chardan PT $4
5. UNH:$UNH Upgraded at Mizuho UBS raising PT 180 to 193 Citi raising PT 164 to 178 Cowen Raising PT 150 to 175 Oppenheimer raising PT 161 to 171

 

DOWNGRADES

4. FCX:$FCX downgraded to Sell at Berenberg

 

EARNINGS

 

Trending Social Alerts

1. USO:OPEC agrees to cut output by 1.2M barrels per day – Bloomberg citing delegate $USO $OIL

 

Trending News Headlines

1. Biotech Stock Mailbag: Looking for an investable idea in Alzheimer’s minefield

TheStreet’s Adam Feuerstein answers reader questions about biotech stocks.

2. Javier Blas on Twitter

“BOOM!!!! #OPEC deal — more on @TheTerminal #OOTT”

3. OPEC Cut Output in Bid to End Record Glut

The reduction will take 1.2 million barrels a day from the market

4. OPEC Said Close to Deal on First Oil Supply Cut in Eight Years

OPEC is near an agreement to cut production for the first time in eight years, sending oil prices surging on optimism a deal with start to drain record global inventories.

5. OPEC agrees first oil output cuts since 2008: source

The Organization of the Petroleum Exporting Countries has agreed its first oil output cuts since 2008, an OPEC source told Reuters on Wednesday.

6. Challenges on Twitter

“ABONNÉS – Apple et SpaceX : coup double pour STMicroelectronics

7. Oil prices surge 7% as source says OPEC has agreed to plan to cut output

Oil prices jumped to a five-week high as oil producers appeared set to agree to a production cut that could be bigger than expected.

8. GoPro to Cut 15% of Jobs Amid Restructuring

GoPro plans to restructure its business, cutting about 15% of its workforce in an effort to lower expenses as it seeks profitability.

9. Philip Morris CEO looks towards phasing out cigarettes: BBC

Philip Morris International (PM.N), the world’s largest international tobacco company, could eventually stop selling cigarettes, its chief executive told the BBC on Wednesday, as it launched its alternative product IQOS in Britain.

10. Press Release | Spark Therapeutics

PHILADELPHIA , Nov. 30, 2016 (GLOBE NEWSWIRE) — Spark Therapeutics (NASDAQ:ONCE), a fully integrated gene therapy company dedicated to challenging the inevitability of genetic disease, announced today that Katherine High , M.D., president and chief scientific officer of Spark Therapeutics , and Lindsey A. George , M.D., hematologist and attending physician at the Children’s Hospital of Philadelphia , will present updated Phase 1/2 clinical trial data for SPK-9001 in hemophilia B at the 58th American Society of Hematology (ASH) Annual Meeting in San Diego .

Technology News

    It consists of one HTML and one CSS file both pasted below and also.
    The exact functionality is unknown but it getting access to VirtualAlloc in and goes from there.
    I had to break the thecode line in two in order to post remove in the middle to restore it.
    A landmark bill which sets out and governs the powers available to the police security and intelligence agencies to gather and access electronic communications has received Royal Assent.
    In receiving Royal Assent the government has fulfilled its commitment to pass the legislation before the Data Retention and Investigatory Powers Act DRIPA sunsets on December.
    I want to pay tribute to the independent reviewers organisations and Parliamentarians of all parties for their rigorous scrutiny of this important law which is vital for the safety and security of our families communities and country.
    On Tue Nov at firstwatch at wrote This is an Javascript exploit Thanks.
    I pointed some folks on irc to this mail and Daniel Veditz Mozilla Security Team said the Firefox team was sent a copy of that this morning.
    And somewhere in there people will look at the bug and see whether they think it really does apply to Tor Browser.
    You will now receive the Game Plan newsletter The fights expected to play out in the coming months in Senate confirmation hearings and through executive action legislation and litigation also will set up an early test of relationship with Silicon Valley giants including Apple and Alphabet Google.
    James Comey director of the Federal Bureau of Investigation has said he also wants to renew a debate early next year about whether Apple and other companies can resist court warrants seeking to unlock encrypted communications.
    While the FBI dropped that case against Apple after buying a tool to hack into the phone the increasing use of encryption on mobile devices and messaging services remains a challenge to national security and law enforcement agencies.
    Image copyrightThinkstockImage caption The UK internet service providers will need to install new equipment to log their customers net habits The Investigatory Powers Bill will get royal assent on Tuesday.
    The fact that it has attracted more than signatures means that it will get debated in Parliament but there seems little chance of ministers taking any more notice than they did of the call for an exploration vessel to be named Boaty McBoatface.
    Image copyrightGetty ImagesThe most contentious part of the forthcoming law is a requirement that communication providers keep a log of their customers net browsing behaviour for a year.
    The National Highway Traffic Safety Administration NHTSA said in a letter to GM that it was permissible for the automaker to automatically activate hazard lights if a driver fails to respond to alerts by a vehicle that has brought itself to a stop but it raised concerns that the system is safe.
    GM monitoring system has facial recognition software that can detect if a driver is falling asleep or not paying attention spokesman Kevin Kelly said Monday.
    Concerns about vehicles that drive themselves for limited periods were raised after the May death of Ohio technology company owner Joshua Brown in a Tesla Motors Inc Model S while the car Autopilot system was engaged.
    Well I do not need to ask you because the government is passing a law about to finish its final stages in parliament that will force your internet service provider whether it be Virgin Media Sky or BT to keep that list for you.
    Would you then be surprised to hear that in parliament on Monday the chief executive of TalkTalk Dido Harding now a Conservative baroness and voted in favour of storing her own web histories so they could be handed over to the police on demand.
    Would you be equally surprised that while Diane Abbott the shadow home secretary said on Tuesday that the new law the investigatory powers bill was and that the legislation her Labour party colleagues in the House of Lords were voting with the Tory government against a Liberal Democrat amendment that would have stopped connection ICRs aka your web history being stored by the internet companies.
    Rudd the UK Home Secretary described the Investigatory Powers Bill as.
    She is right only in that it sets out one of the worst examples in the democratic world of government trampling on human rights online legalising the sweeping abuses under PRISM revealed by Edward Snowden.
    everything you do online can be spied on by a long list of government agencies will inevitably take away some of our precious freedom to use the web as a space for exploration and dissent.
    The feature is new to mobile devices though Twitter previously brought this design to the web in June.
    The new design also includes conversation counts so you can see which tweets are generating the most abuse and harassment at a glance.
    Twitter is a free app and you can download it on Android and iOS if you want.

 

PRE-MARKET | November 29, 2016 | $TSLA, $AAPL #trade, $GOLD, $USO, $CL_F, $JAZZ, $PFE, $REGN, $IBB

PRE-MARKET | November 29, 2016 | $TSLA, $AAPL #trade, $GOLD, $USO, $CL_F, $JAZZ, $PFE, $REGN, $IBB

PRE-MARKET MOVERS

 

UPGRADES

2. BAC:$BAC Upgrade DJ Bank of America Raised to Outperform From Market Perform by Keefe Bruyette & Woods Tue Nov 29 05:46:52 2016 EDT
4. PFE:$pfe upgraded to overweight by Barclays
5. TSCO:$TSCO gapping higher on zero volume on an upgrade from Northcoast , upgrading to BUY with a $102 price tgt
6. VCYT:$VCYT upgraded to Buy from Neutral at Janney

 

DOWNGRADES

11. SGEN:$SGEN downgraded to Equal-Weight from Overweight at Barclays
14. VRTX:$VRTX downgraded to Equal-Weight from Overweight at Barclays
15. WEN:$WEN downgraded to Neutral at Goldman Sachs
17. X:$X downgraded to Hold at Argus Research

 

EARNINGS

 

Trending Social Alerts

2. X:Good start to the day with $X down over $1.20,
3. TIF:Tiffany Q3 EPS $0.76, Revenue $949M vs $927M Est $TIF
4. MTSC:$MTSC Halted, news pending
8. CL_F:Crazy 80 cent drop in crude futures $CL_F
9. USO:iranian oil minister says will not cut production. $USO $CL_F

 

Trending News Headlines

1. CytRx CEO Pockets Millions of Dollars as Failed Sarcoma Drug Moves to FDA

CytRx announced a plan Tuesday to seek U.S. marketing approval of aldoxorubicin based more on hocus-pocus than credible science.

2. In OPEC Poker Game, Iran and Iraq Call Saudi Arabia’s Bluff

For decades, Saudi Arabia has had its way at OPEC. All of a sudden the position has turned: Riyadh finds its power waning against a resurgent Iran and Iraq.

3. Exclusive: ECB ready to buy more Italian bonds if referendum rocks market – sources

The European Central Bank is ready to temporarily step up purchases of Italian government bonds if the result of a crucial referendum on Sunday sharply drives up borrowing costs for the euro zone’s largest debtor, central bank sources told Reuters.

4. Don’t Be Surprised When Activision Blizzard CEO Does a Big Deal

Activision Blizzard Inc. is giving Chief Executive Officer Robert Kotick major financial incentives to do deals — a form of compensation that’s become increasingly unusual amid investor scrutiny.

5. Iran, Iraq at loggerheads with Saudis ahead of OPEC meeting

Iran and Iraq are resisting pressure from Saudi Arabia to curtail oil production, making it hard for the Organization of the Petroleum Exporting Countries to reach a global output-limiting deal when it meets on Wednesday.

6. Amazon Said to Plan Premium Alexa Speaker With Large Screen

Amazon.com Inc. is developing a premium Echo-like speaker with a screen, a sign the world’s largest online retailer is trying to capitalize on the surprise success of its voice-controlled home gadgets and fend off competition from Google and Apple Inc.

7. Jeweler Tiffany posts first sales rise in eight quarters

Tiffany & Co (TIF.N) reported its first rise in sales in eight quarters as strong sales in Japan and China more than offset a decline in the United States, its biggest market.

8. In OPEC’s High-Stakes Poker Game, Iran and Iraq Call Saudi Bluff

For decades, Saudi Arabia has had its way at OPEC. All of a sudden the position has turned: Riyadh finds its power waning against a resurgent Iran and Iraq.

9. Trillium Therapeutics Announces Conference Call and Webcast on December 5th to Discuss TTI-621 Data Presented at ASH

Trillium Therapeutics Inc. , a clinical stage immuno-oncology company developing innovative therapies for the treatment of cancer, today announced that it will host a conference call and webcast at 8:30 …

Technology News

    What that turned into was a state representative in the House in Colorado proposing actual legislation to prevent people from using their food stamps to buy marijuana based on something that had just never happened Coler says.
    It was just anybody with a blog can get on there and find a big huge Facebook group of kind of rabid Trump supporters just waiting to eat up this red meat that they about to get served Coler says.
    So it seems to be a kind of arbitrary step that they taking either based on I do know if it was my reputation within the industry or specifically the Denver Guardian site that angered them or I do know what it is but back to your question there hundreds of people that will work with me.
    ET CNN has acquired startup Beme a social media app launched last year by popular YouTube star Casey Neistat the network announced Monday.
    The Beme app which allowed users to shoot and share quick unedited video clips had an auspicious start thanks in large part to diehard social media following.
    The Beme app will be shuttered with the employees joining CNN to form a separate technology unit focusing on the new media venture and wider mobile video efforts.
    Tomorrow the White House will partner with Stanford University and the Chan Zuckerberg Initiative a limited liability corporation launched by the CEO of Facebook and his wife to the Summit on Poverty and Opportunity a event held on the campus.
    The list of attendees and speakers also includes CEO Steve Ballmer White House CTO Megan Smith formerly a top executive at Google Martin Ford author of two books on automation including Rise of the Robots Marian Edelman founder of the Defense Fund Nobel economist Ken Arrow and Bryan Desloge president of the National Association of Counties who backed Donald Trump in the presidential election and has participated in a previous White House summit on poverty.
    This event comes at a time when tech moguls like Mark Zuckerberg and Sean Parker have been subject to increased scrutiny for their approach to doing good which eschews nonprofit foundations for traditional investment vehicles labeled as philanthropy.
    CNN announced on Monday that it had agreed to acquire the technology and talent behind Beme the social media app built and started by Neistat and Matt Hackett a former vice president of engineering at Tumblr.
    Beme saw early traction especially among avid personal following but failed to capture a large part of the social sharing market amid competitors like Instagram Facebook and others.
    AMC the network known for the hit series Walking Dead announced this month that it had taken a minority stake in Funny or Die the digital comedy site founded by Will Ferrell and Adam McKay.
    What that turned into was a state representative in the House in Colorado proposing actual legislation to prevent people from using their food stamps to buy marijuana based on something that had just never happened Coler says.
    It was just anybody with a blog can get on there and find a big huge Facebook group of kind of rabid Trump supporters just waiting to eat up this red meat that they about to get served Coler says.
    So it seems to be a kind of arbitrary step that they taking either based on I do know if it was my reputation within the industry or specifically the Denver Guardian site that angered them or I do know what it is but back to your question there hundreds of people that will work with me.
    At an event in New York City today AT T has announced that its mobile subscribers will be able to stream its new DirecTV Now service without using their data.
    AT T is just the latest to challenge the ruling but with a new and likely more lenient administration at least on net neutrality the bet to go against the FCC may just pay off.
    DirecTV Now will be available on November and will offer over channels starting at a month for a limited time.
    The incident is one of several examples including threats of regulation and attempts to prosecute chief executive Mark Zuckerberg of how Germany has become an important test case globally for how the social network polices what may be published online and how it should respond to inappropriate and illegal content.
    a mural by Günther Schaefer that depicts a Star of David on a German flag is painted on the remains of the Berlin Phil Moore for The New York Times recognize that this is a work in progress Richard Allen director of policy in Europe said in an interview.
    Jun recently filed a complaint with Munich authorities seeking prosecution of Zuckerberg and other senior Facebook executives on charges they failed to sufficiently tackle the widespread wave of hate speech in Germany.
    At an event in New York City today AT T has announced that its mobile subscribers will be able to stream its new DirecTV Now service without using their data.
    AT T is just the latest to challenge the ruling but with a new and likely more lenient administration at least on net neutrality the bet to go against the FCC may just pay off.
    DirecTV Now will be available on November and will offer over channels starting at a month for a limited time.
    Tomorrow the White House will partner with Stanford University and the Chan Zuckerberg Initiative a limited liability corporation launched by the CEO of Facebook and his wife to the Summit on Poverty and Opportunity a event held on the campus.
    The list of attendees and speakers also includes CEO Steve Ballmer White House CTO Megan Smith formerly a top executive at Google Martin Ford author of two books on automation including Rise of the Robots Marian Edelman founder of the Defense Fund Nobel economist Ken Arrow and Bryan Desloge president of the National Association of Counties who backed Donald Trump in the presidential election and has participated in a previous White House summit on poverty.
    This event comes at a time when tech moguls like Mark Zuckerberg and Sean Parker have been subject to increased scrutiny for their approach to doing good which eschews nonprofit foundations for traditional investment vehicles labeled as philanthropy.
    In April of this year Steve Hill executive director of the Nevada Office of Economic Development GOED wrote an email to Jude Hurin the administrator in charge of autonomous vehicle AV regulation at the DMV.
    Otto had now come full circle from a tiny startup intent on disrupting taxis in Las Vegas to maverick autonomous truckers to a key part of the biggest company on the planet.
    The testing facility a wholly owned subsidiary called Nevada ATCF LLC received its license from the DMV at the end of September and is currently hiring staff and remodeling a building in southwest Las Vegas.

 

PRE-MARKET | November 28, 2016 | $AMZN, $DG, $TIME, $CUBA, $DTLR, $DX, $COP, $TWTR, $AAPL, $NFLX

PRE-MARKET | November 28, 2016 | $AMZN, $DG, $TIME, $CUBA, $DTLR, $DX, $COP, $TWTR, $AAPL, $NFLX

PRE-MARKET MOVERS

 

UPGRADES

5. FCAU:ISI $FCAU “the day has come to upgrade FCA from Sell to Buy”
7. NTES:$NTES upgraded to Buy at Jefferies

 

DOWNGRADES

4. CBRL:$CBRL downgraded to Hold at Maxim Group
7. DRI:$DRI downgraded to Hold at MaximGroup
14. PNRA:$PNRA downgraded to Neutral at Wedbush – PT $220
18. WFC:$WFC downgraded to Hold @ Jefferies

 

Trending Social Alerts

1. REPH:$REPH Reports Positive Top-Line Results From Pivotal Phase 3 Trial of IV Meloxicam
2. HTBX:$HTBX continues its monster run… gapping up 22% in premarket
3. CTSH:$CTSH – Elliott Mgmt. sees $80-$90/share, guessing it is them that are the proud owners of the 30,000 April $55 calls bought recently
5. IDRA:$REPH $IDRA halted

 

Trending News Headlines

1. Recro Pharma Reports Positive Top-Line Results from Pivotal Phase III Clinical Trial of IV Meloxicam

IV Meloxicam Achieves Primary Endpoint of Statistically Significant Reduction in SPID24 in Patients with Acute Postoperative Pain Following Abdominoplasty Surgery

2. OPEC makes last-ditch bid to save oil deal as tensions grow

OPEC was trying on Monday to rescue a deal to limit oil output as tensions grew among the producer group and non-OPEC member Russia, with top exporter Saudi Arabia saying markets would rebalance even without an agreement.

3. Actelion’s ambitious independent-minded CEO will drive up takeover price

Actelion Chief Executive Jean-Paul Clozel’s desire to keep Europe’s biggest biotech company independent after building it from scratch, means Johnson & Johnson will have to pay a steep premium if a takeover is to succeed.

4. OPEC May Give Trump Energy Goals a Boost

President-elect Donald Trump says he plans to make America energy independent. He may receive an unintended boost next week in the form of an oil production cut by OPEC, which could raise crude prices.

5. Oil Investors Have $490 Billion Riding on Big OPEC Decision

After two tough years of falling oil prices and company valuations, investors in the world’s biggest energy producers have some cause for hope as crude prices continue their recovery from a 12-year low. They will be looking to OPEC not to dash it.

6. Time Inc. rejects buyout bid from billionaire Edgar Bronfman Jr.

Edgar Bronfman Jr. is making a bid to buy Time Inc., publisher of People, Time and Sports Illustrated, The Post has learned. Bronfman, who is teaming up with Len Blavatnik’s Access Industries, rece…

7. OPEC’s Last Cut Shows Oil Market Could Get a Whole Lot Messier

Anyone planning to trade the outcome of this week’s OPEC meeting might consider the lessons of the group’s last production cut. Then take a deep breath.

Technology News

    What that turned into was a state representative in the House in Colorado proposing actual legislation to prevent people from using their food stamps to buy marijuana based on something that had just never happened Coler says.
    It was just anybody with a blog can get on there and find a big huge Facebook group of kind of rabid Trump supporters just waiting to eat up this red meat that they about to get served Coler says.
    So it seems to be a kind of arbitrary step that they taking either based on I do know if it was my reputation within the industry or specifically the Denver Guardian site that angered them or I do know what it is but back to your question there hundreds of people that will work with me.
    If readers had the opportunity to visit the site it would have become instantly apparent that this group of ostensible experts far more resembles amateur peddlers of primitive shallow propagandistic clichés than serious substantive analysis and expertise that it has a blatant demonstrable bias in promoting narrative about the world and that it is engaging in extremely dubious McCarthyite tactics about a wide range of critics and dissenters.
    It actively calls on Congress and the White House to work our European allies to disconnect Russia from the SWIFT financial transaction system effective immediately and lasting for at least one year as an appropriate response to Russian manipulation of the.
    Even more disturbing than the shoddy journalism in this instance is the broader trend in which any wild conspiracy theory or McCarthyite attack is now permitted in discourse as long as it involves Russia and Putin just as was true in the when stories of how the Russians were poisoning the water supply or infiltrating American institutions were commonplace.
    What that turned into was a state representative in the House in Colorado proposing actual legislation to prevent people from using their food stamps to buy marijuana based on something that had just never happened Coler says.
    It was just anybody with a blog can get on there and find a big huge Facebook group of kind of rabid Trump supporters just waiting to eat up this red meat that they about to get served Coler says.
    So it seems to be a kind of arbitrary step that they taking either based on I do know if it was my reputation within the industry or specifically the Denver Guardian site that angered them or I do know what it is but back to your question there hundreds of people that will work with me.
    For nearly five decades Myanmar lived under military dictatorships that suppressed all forms of dissent and limited free speech leading to US and European sanctions that largely cut off the country from the rest of the world.
    Dozens of people have been jailed for what written on Facebook though human rights groups say the exact number is unknown as many arrests go unreported especially outside the city centers where the legal system is not as closely monitored.
    Facebook says constantly thinking about ways to improve digital literacy and that it will soon release a security awareness campaign designed specifically for Myanmar and that worked with local civil liberty groups to publish a pamphlet that includes a translated and illustrated version of its community standards.
    You will now receive the Game Plan newsletter vote to leave the European Union has threatened to upend arrangements with one of its largest trading partners while Donald election victory might undermine status as a haven for companies in Europe.
    Local supporters fear that Apple may grow impatient prompting community leaders to organize a rally in favor of the project earlier this month.
    was a gesture of solidarity with Apple to show that the vast majority of people in the area support the project said Peter Feeney a local councilor with Prime Minister Enda Fine Gael party.
    A number of the allies that PropOrNot lists on its the investigative blogger Eliot Higgins who runs a research entity called BellingCat that has used crowdsourcing to track Russian government activity in they have never heard of the group.
    For example the article refers to what it calls useful idiots as being part of this campaign a group that includes any accounts which regurgitate Russian themes and without necessarily taking direction from Russia or collaborating in a fully informed manner.
    The PropOrNot article which the Post said it was given prior to publication reportedly says the Russian campaign worked by harnessing the online fascination with content that is surprising and emotionally potent and tracks with popular conspiracy theories.
    One of the themes that has emerged during the controversy over and its role in the election of Donald Trump is the idea that Russian agents of various kinds helped hack the process by fueling this barrage of false news.
    A number of the that PropOrNot lists on its the investigative blogger Eliot Higgins who runs a research entity called BellingCat that has used crowdsourcing to track Russian government activity in they have never heard of the group.
    The PropOrNot article which the Post said it was given prior to publication reportedly says the Russian campaign worked by the online fascination with content that is surprising and emotionally potent and tracks with popular conspiracy.
    This trend continued into Black Friday as the sales event is currently tracking to bring in billion in revenue which is up percent.
    toys included Lego Creator Sets electric scooters from Razor Nerf Guns DJI Phantom Drones and Barbie Dreamhouse.
    We still expect Cyber Monday to surpass Black Friday and become the largest online sales day in history with.
    The round which was led by Ashton Kutcher and Guy Sound Ventures brings total raise to date to million.
    That has led it to attract a number of companies to sign up for its paid service including Google Pinterest Facebook NBC Universal Philips Deloitte Telerik Fyber Airpush Chartboost Startapp SendGrid and others.
    Sapir admits to being something of an underdog in the space but one now rapidly growing after nearly having to shut down not too long ago when the marketplace failed.

 

PRE-MARKET | November 23, 2016 | $BIIB, $NFLX, $CL_F, $GDX, $GLD, $SLV, $ES_F, $JUNO, $AMZN, $NFLX, $AAPL

PRE-MARKET | November 23, 2016 | $BIIB, $NFLX, $CL_F, $GDX, $GLD, $SLV, $ES_F, $JUNO, $AMZN, $NFLX, $AAPL

PRE-MARKET MOVERS

 

UPGRADES

 

DOWNGRADES

 

EARNINGS

 

Trending Social Alerts
1. LLY:$LLY Solanezumab fails
2. IBB:If U trade actively you need to notice small changes. $ibb did show relative weakness yesterday. Someone always kno…
3. JUNO:$JUNO clinical hold on jcar15
4. AXON:$LLY ↓ 15%, $BIIB ↓ 9%, $AXON ↓ 18% PM
5. ESEA:$ESEA *DJ Euroseas: To Buy Panamax Size Drybulk Carrier for Approximately $4.4 Million >ESEA
6. DE:Deere Q4 earnings: EPS $0.90 Revenue $5.65bln $DE
9. CLRB:$CLRB raises $8m at $1.50, warrants also
10. GDX:@TheTradingNinja $gdx 19.00 Dec 16th puts had bought 3 a week ago Just saw gold now below 1200 $$$$$$$$$$$$$$$$$$$$$$$$$$
11. BIIB:$LLY down 10% pre-market, $BIIB down 4.6% on solanezumab phase 3 failure

 

Trending News Headlines
1. Juno Therapeutics Places JCAR015 Phase II ROCKET Trial on Clinical Hold

Juno Therapeutics, Inc. , a biopharmaceutical company focused on re-engaging the body’s immune system to revolutionize the treatment of cancer, today announced that it has voluntarily placed on hold the Phase II clinical trial of JCAR015 in adult patients with relapsed or refractory B cell acute lymphoblastic

2. Juno Therapeutics CAR-T Study Halts Following Another Additional Patient Death

Juno Therapeutics halted a clinical trial involving its most advanced CAR-T therapy for the second time in five months after another two cancer patients developing brain swelling.

3. Exclusive: ECB seeks to lend out more bonds to avert market freeze – sources

The European Central Bank is looking for ways to lend out more of its huge pile of government debt to avert a freeze in the 5.5 trillion-euro short-term funding market that underpins the financial system, central bank sources told Reuters.

4. Meg Tirrell on Twitter

“$JUNO halts ROCKET trial after two patients get cerebral edema; one died, other expected not to recover”

5. Bio Stocks™ on Twitter

“$LLY ↓ 15%, $BIIB ↓ 9%, $AXON ↓ 18% PM”

6. Eli Lilly’s Alzheimer’s drug fails key clinical trial

Based on the negative study results, Lilly will not pursue regulatory approvals for solanezumab in Alzheimer’s disease.

7. Facebook Said to Create Censorship Tool to Get Back Into China

The social network, blocked in China since 2009, has developed software to keep posts from appearing in users’ news feeds in specific geographic areas, current and former employees said.

8. Eli Lilly and Co – LLY – Stock Quotes

Eli Lilly and Co, LLY real time stock quotes, news, videos at CNBC.com

9. Lilly Announces Top-Line Results of Solanezumab Phase 3 Clinical Trial (NYSE:LLY)

/* Style Definitions */ span.prnews_span { font-size:8pt; font-family:”Arial”; color:black; } a.prnews_a { color:blue; } li.prnews_li { font-size:8pt; font-family:”Arial”; color:black; } p.prnews_p { font-size:0.62em; font-family:”Arial”; color:black; margin:0in; }

10. Lilly Announces Top-Line Results of Solanezumab Phase 3 Clinical Trial

INDIANAPOLIS, Nov. 23, 2016 /PRNewswire/ — Eli Lilly and Company (LLY) today announced that solanezumab did not meet the primary endpoint in the EXPEDITION3 clinical trial, a phase 3 study of solanezumab in people with mild dementia due to Alzheimer’s disease (AD). Patients treated with solanezumab

11. One dead, one dying as Juno’s lead CAR-T turns lethal again; trial halted

Juno’s lead CAR-T drug is killing more patients. Four months after the biotech was forced to scramble to save the program in the wake of three patient deaths, Juno says that one more patient has died of cerebral edema and another is at death’s door. Juno has voluntarily put the

12. Eli Lilly’s Late-Stage Alzheimer’s Trial Fails to Achieve Goal

Eli Lilly’s shares plunge as a closely watched late-stage trial of an Alzheimer’s drug had failed to achieve its goal.

13. Deere Jumps as Profit Forecast Beats Estimates Amid Cost Cuts

Deere & Co. posted quarterly earnings and a 2017 profit forecast that exceeded analysts’ estimates as the world’s largest agricultural equipment maker’s cost-cutting efforts offset some of the effects of lower demand. The shares rose as much as 13 percent in pre-market trading.

14. Shane Blackmon on Twitter

“$JUNO clinicla hold on Phase 2 Rocket Trial”

15. Trump chooses Governor Nikki Haley for U.N. ambassador: news reports

President-elect Donald Trump has chosen South Carolina Governor Nikki Haley, a daughter of immigrants from India who has little international experience, to be U.S. ambassador to the United Nations, The Post and Courier newspaper and other media reported on Wednesday.

Technology News
    Devorah Heitner author of and founder of Raising Digital Natives an Evanston provider of consulting services to schools suggests parents pick up on their interests and help them to find and evaluate news on the topic online.
    Many students multitask by texting reading and watching video at once hampering the concentration needed to question content and think deeply says Yalda Uhls a research psychologist at the Digital Media Center at the University of California Los Angeles.
    Talk with teens about information found online and ask did you click on that says Will Colglazier a history teacher at Aragon High School in San Mateo who is helping test Stanford University teaching materials aimed at remedying the problem.
    Devorah Heitner author of and founder of Raising Digital Natives an Evanston provider of consulting services to schools suggests parents pick up on their interests and help them to find and evaluate news on the topic online.
    Many students multitask by texting reading and watching video at once hampering the concentration needed to question content and think deeply says Yalda Uhls a research psychologist at the Digital Media Center at the University of California Los Angeles.
    Talk with teens about information found online and ask did you click on that says Will Colglazier a history teacher at Aragon High School in San Mateo who is helping test Stanford University teaching materials aimed at remedying the problem.
    The social network has quietly developed software to suppress posts from appearing in news feeds in specific geographic areas according to three current and former Facebook employees who asked for anonymity because the tool is confidential.
    Instead it would offer the software to enable a third party in this case most likely a partner Chinese company to monitor popular stories and topics that bubble up as users share them across the social network the people said.
    More broadly China has streamlined and tightened its controls over the internet under President Xi targeting influential social media celebrities and adding new reviews to popular online video sites.
    When it comes to evaluating information that flows across social channels or pops up in a Google search young and otherwise students can easily be duped finds a new report from researchers at Stanford Graduate School of Education.
    At the high school level one assessment tested whether students were familiar with key social media conventions including the blue checkmark that indicates an account was verified as legitimate by Twitter and Facebook.
    The researchers found that high production values links to reputable news organizations and polished pages had the ability to sway students into believing without very much skepticism the contents of the site.
    If ever answered questions like these on one of the free personality quizzes floating around Facebook have learned known as your Ocean score How you rate according to the big five psychological traits of Openness Conscientiousness Extraversion Agreeableness and Neuroticism.
    Cambridge is reportedly backed by Robert Mercer a hedge fund billionaire and a major Republican donor a key board member is Stephen Bannon the head of Breitbart News who became campaign chairman and is set to be his chief strategist in the White House.
    Ever since the advertising executive Lester Wunderman coined the term in the ability to target specific consumers with ads rather than blanketing the airwaves with mass appeals and hoping the right people will hear them has been the holy grail.
    AppNexus operator of one of the biggest digital advertising services has barred Breitbart News from using its tools because the conservative online publisher violated its hate speech rules.
    Breitbart News Network continues to experience exceptional growth having attracted over million unique visitors in the last thirty days alone Solov also said in his statement.
    The online publication has been criticized for incendiary articles such as one that warns of Muslim invaders and another that dubs conservative thinker Bill Kristol a Renegade Jew.
    If ever answered questions like these on one of the free personality quizzes floating around Facebook have learned known as your Ocean score How you rate according to the big five psychological traits of Openness Conscientiousness Extraversion Agreeableness and Neuroticism.
    Cambridge is reportedly backed by Robert Mercer a hedge fund billionaire and a major Republican donor a key board member is Stephen Bannon the head of Breitbart News who became campaign chairman and is set to be his chief strategist in the White House.
    Ever since the advertising executive Lester Wunderman coined the term in the ability to target specific consumers with ads rather than blanketing the airwaves with mass appeals and hoping the right people will hear them has been the holy grail.
    Two years ago Ben Kaufman of consumer product startup Quirky delivered one of the most awkward and candid interviews ever witnessed at annual Brainstorm Tech conference.
    Before it created BuzzFeed Product Lab commerce efforts revolved around affiliate links where the media company gets paid for driving sales to third party sites.
    Now BuzzFeed is chasing the holy grail of commerce an area that has eluded social platforms like Facebook for years and killed many other startups tackling the category along the way.
    Nathaniel Faggioli the company chief operating officer a former Goldman Sachs banker has pushed his employees to find ways to improve its margins as the startup tries to attract another round of financing according to the people.
    Meanwhile Munchery line cooks in San Francisco its flagship market stayed up until assembling Vietnamese caramel chicken roasted half game hen and beef pho said the current and former employees.
    From September to July Munchery San Francisco kitchen made about dishes an entree or a side that never got sold according to an internal financial document and interviews with who asked to remain anonymous out of fear of reprisal from their former employer.
    The social network has quietly developed software to suppress posts from appearing in news feeds in specific geographic areas according to three current and former Facebook employees who asked for anonymity because the tool is confidential.
    Instead it would offer the software to enable a third party in this case most likely a partner Chinese company to monitor popular stories and topics that bubble up as users share them across the social network the people said.
    More broadly China has streamlined and tightened its controls over the internet under President Xi targeting influential social media celebrities and adding new reviews to popular online video sites.