PRE-MARKET | December 01, 2016 | $FIT, $BLUE, $MCD, $DG, $DRYS, $KR, $ES_F, $CL_F, $ESRX

PRE-MARKET | December 01, 2016 | $FIT, $BLUE, $MCD, $DG, $DRYS, $KR, $ES_F, $CL_F, $ESRX

PRE-MARKET MOVERS

 

UPGRADES

3. DE:$DE upgraded to Buy at BankofAmerica
8. SKX:$SKX upgraded to Buy at Buckingham

 

DOWNGRADES

3. MCD:$MCD downgraded to Neutral at Guggenheim
7. WFC:$WFC downgraded to Neutral at Susquehanna

 

EARNINGS

 

Trending Social Alerts

1. DG:Dollar General Q3 EPS $0.84 vs $0.93, Revenue $5.32B vs $5.37B Est $DG
2. KR:Kroger meets on earnings. Guidance merely in-line. Food deflation still an issue. Good for shoppers. Not investors. $KR down 3% #premarket.
4. ESRX:We’ve been selling high-deductible plans to people who can’t afford them, $ESRX CMO Steve Miller tells @matthewherper at #ForbesHealth
8. PFE:$PFE Lyrica Phase 3 Trial in Pediatric Epilepsy Meets Primary Endpoint

 

Trending News Headlines

1. Apple Said to Fly Drones to Improve Maps Data and Catch Google

Apple Inc. plans to use drones and new indoor navigation features to improve its Maps service and catch longtime leader Google, according to people familiar with the matter.

2. Barbarian Capital on Twitter

“Life comes at you fast… $GS”

3. Bluebird, Celgene T-Cell Therapy Eliminates Multiple Myeloma with Minimal Side Effects

‘We’re seeing impressive, early responses with BB2121 without the toxicity,’ says Bluebird CEO Nick Leschly.

4. Russia’s Pledge to OPEC Will Mean ‘Herding Cats’ to Deliver Cuts

Russia has committed to cooperate with OPEC by cutting as much as 300,000 barrels a day from its oil output but offered no clear method for enforcement, creating uncertainty about how easily the reduction can be delivered.

5. DryShips Announces Bank Update

DryShips Inc. , an international owner of drybulk carriers and offshore support vessels, announced today that a company controlled by Mr. George Economou, our Chairman and CEO has become the lender of …

6. blue-ex992_41.pptx.htm

EORTC-NCI-AACR Molecular Targets and Cancer Therapies Symposium December 1, 2016 Exhibit 99.2

7. Andy Biotech on Twitter

“$BLUE — The 1PR in the low dose cohort has already relapsed after ~9wks”

8. Early movers: DG, LE, MCD, CLC, MLBY, DIS, BOX, PVH & more

Some of the names on the move ahead of the open.

9. Gold Slides to 10-Month Low as Fund Selling Spree Continues

Gold sank to the lowest in almost 10 months and funds backed by the metal continued to shrink on speculation the U.S. economy is strengthening.

10. China Stands to Gain From OPEC Deal

For China’s beleaguered oil sector, a deal by the Organization of the Petroleum Exporting Countries to cut output could offer a lifeline to an industry that has been hammered by low prices—and may also hasten its shift away from a heavy reliance on Saudi crude.

11. Bernstein ‘Surprisingly’ Likes the Idea of Disney (DIS) Buying Netflix (NFLX)

In a note this morning Bernstein analyst Todd Juenger said they are ‘surprisingly’ open to Disney (NYSE: DIS) acquiring Netflix (NASDAQ:…

Technology News

    by Jeff Barr on NOV in AWS re Invent Polly Permalink As I was getting ready to write this post I thought back to my childhood largely spent watching TV and some of the popular computer and robot voices of the and.
    In just a few minutes pleasant memories of Lost in Space the original Star Trek Computer and Rosie from The Jetsons all came to mind.
    We asked each speaker to pronounce a myriad of representative words and phrases in their chosen language and then disassembled the audio into sound units known as diphones.
    Hotz framed the software called Open Pilot as an source alternative to during a press event that was held in a San Francisco house that serves as headquarters.
    Earlier this year Hotz announced ambitions to create and sell a kit called that could add capabilities to Honda Civics and some Acura cars.
    strongly encourage you to delay selling or deploying your product on the public roadways unless and until you can ensure it is safe Paul Hemmersbaugh chief counsel wrote in the letter.
    WASHINGTON A effort in the Senate to block or delay rule changes that would expand the government hacking powers failed Wednesday despite concerns the changes would jeopardize the privacy rights of innocent Americans and risk possible abuse by the incoming administration of Donald Trump.
    Democratic Senator Ron Wyden attempted three times to delay the changes which will take effect on Thursday and allow judges will be able to issue search warrants that give the FBI the authority to remotely access computers in any jurisdiction potentially even overseas.
    In an effort to address concerns Assistant Attorney General Leslie Caldwell wrote a blog post this week arguing that the benefits given to authorities from the rule changes outweighed any potential for unintended harm.
    Its members spread coded hate speech openly antagonize other Redditors and break the most basic rules with impunity while moderators feel the brunt of the abuse and Reddit leadership fail to adequately address the problem.
    When asked what instances merit intervention by admins the Reddit spokesperson gave three examples targeted harassment or doxxing of an individual two mod teams requesting mediation to resolve a conflict with each other or the breach of a site rule.
    And where a prejudicial agenda is concerned the and regressive beliefs held by own transition team are reflected in users who gleefully attack people on the basis of their religion race heritage sexuality gender identity or political leanings.
    By.
    ET AppNexus an automated technology company has confidentially filed paperwork for an initial public offering that is likely to come in the second quarter of according to people familiar with the matter.
    The company which was valued at billion in a funding round could seek a valuation between billion and billion in the offering though pricing talk is still fluid the people said.
    by Jeff Barr on NOV in AWS re Invent Polly Permalink As I was getting ready to write this post I thought back to my childhood largely spent watching TV and some of the popular computer and robot voices of the and.
    In just a few minutes pleasant memories of Lost in Space the original Star Trek Computer and Rosie from The Jetsons all came to mind.
    We asked each speaker to pronounce a myriad of representative words and phrases in their chosen language and then disassembled the audio into sound units known as diphones.
    Its members spread coded hate speech openly antagonize other Redditors and break the most basic rules with impunity while moderators feel the brunt of the abuse and Reddit leadership fail to adequately address the problem.
    When asked what instances merit intervention by admins the Reddit spokesperson gave three examples targeted harassment or doxxing of an individual two mod teams requesting mediation to resolve a conflict with each other or the breach of a site rule.
    And where a prejudicial agenda is concerned the and regressive beliefs held by own transition team are reflected in users who gleefully attack people on the basis of their religion race heritage sexuality gender identity or political leanings.
    Read comments from top tech and industry leaders.

 

11. US JOBLESS CLAIMS

 

PRE-MARKET | November 30, 2016 | #OPEC, $CL_F, $SCO, $USO, $ES_F, $TLT, $AMZN, $SPLK, $GE, $GPRO

PRE-MARKET | November 30, 2016 | #OPEC, $CL_F, $SCO, $USO, $ES_F, $TLT, $AMZN, $SPLK, $GE, $GPRO

PRE-MARKET MOVERS

 

UPGRADES

1. ABUS:$ABUS upgraded to Buy from Neutral at Chardan PT $4
5. UNH:$UNH Upgraded at Mizuho UBS raising PT 180 to 193 Citi raising PT 164 to 178 Cowen Raising PT 150 to 175 Oppenheimer raising PT 161 to 171

 

DOWNGRADES

4. FCX:$FCX downgraded to Sell at Berenberg

 

EARNINGS

 

Trending Social Alerts

1. USO:OPEC agrees to cut output by 1.2M barrels per day – Bloomberg citing delegate $USO $OIL

 

Trending News Headlines

1. Biotech Stock Mailbag: Looking for an investable idea in Alzheimer’s minefield

TheStreet’s Adam Feuerstein answers reader questions about biotech stocks.

2. Javier Blas on Twitter

“BOOM!!!! #OPEC deal — more on @TheTerminal #OOTT”

3. OPEC Cut Output in Bid to End Record Glut

The reduction will take 1.2 million barrels a day from the market

4. OPEC Said Close to Deal on First Oil Supply Cut in Eight Years

OPEC is near an agreement to cut production for the first time in eight years, sending oil prices surging on optimism a deal with start to drain record global inventories.

5. OPEC agrees first oil output cuts since 2008: source

The Organization of the Petroleum Exporting Countries has agreed its first oil output cuts since 2008, an OPEC source told Reuters on Wednesday.

6. Challenges on Twitter

“ABONNÉS – Apple et SpaceX : coup double pour STMicroelectronics

7. Oil prices surge 7% as source says OPEC has agreed to plan to cut output

Oil prices jumped to a five-week high as oil producers appeared set to agree to a production cut that could be bigger than expected.

8. GoPro to Cut 15% of Jobs Amid Restructuring

GoPro plans to restructure its business, cutting about 15% of its workforce in an effort to lower expenses as it seeks profitability.

9. Philip Morris CEO looks towards phasing out cigarettes: BBC

Philip Morris International (PM.N), the world’s largest international tobacco company, could eventually stop selling cigarettes, its chief executive told the BBC on Wednesday, as it launched its alternative product IQOS in Britain.

10. Press Release | Spark Therapeutics

PHILADELPHIA , Nov. 30, 2016 (GLOBE NEWSWIRE) — Spark Therapeutics (NASDAQ:ONCE), a fully integrated gene therapy company dedicated to challenging the inevitability of genetic disease, announced today that Katherine High , M.D., president and chief scientific officer of Spark Therapeutics , and Lindsey A. George , M.D., hematologist and attending physician at the Children’s Hospital of Philadelphia , will present updated Phase 1/2 clinical trial data for SPK-9001 in hemophilia B at the 58th American Society of Hematology (ASH) Annual Meeting in San Diego .

Technology News

    It consists of one HTML and one CSS file both pasted below and also.
    The exact functionality is unknown but it getting access to VirtualAlloc in and goes from there.
    I had to break the thecode line in two in order to post remove in the middle to restore it.
    A landmark bill which sets out and governs the powers available to the police security and intelligence agencies to gather and access electronic communications has received Royal Assent.
    In receiving Royal Assent the government has fulfilled its commitment to pass the legislation before the Data Retention and Investigatory Powers Act DRIPA sunsets on December.
    I want to pay tribute to the independent reviewers organisations and Parliamentarians of all parties for their rigorous scrutiny of this important law which is vital for the safety and security of our families communities and country.
    On Tue Nov at firstwatch at wrote This is an Javascript exploit Thanks.
    I pointed some folks on irc to this mail and Daniel Veditz Mozilla Security Team said the Firefox team was sent a copy of that this morning.
    And somewhere in there people will look at the bug and see whether they think it really does apply to Tor Browser.
    You will now receive the Game Plan newsletter The fights expected to play out in the coming months in Senate confirmation hearings and through executive action legislation and litigation also will set up an early test of relationship with Silicon Valley giants including Apple and Alphabet Google.
    James Comey director of the Federal Bureau of Investigation has said he also wants to renew a debate early next year about whether Apple and other companies can resist court warrants seeking to unlock encrypted communications.
    While the FBI dropped that case against Apple after buying a tool to hack into the phone the increasing use of encryption on mobile devices and messaging services remains a challenge to national security and law enforcement agencies.
    Image copyrightThinkstockImage caption The UK internet service providers will need to install new equipment to log their customers net habits The Investigatory Powers Bill will get royal assent on Tuesday.
    The fact that it has attracted more than signatures means that it will get debated in Parliament but there seems little chance of ministers taking any more notice than they did of the call for an exploration vessel to be named Boaty McBoatface.
    Image copyrightGetty ImagesThe most contentious part of the forthcoming law is a requirement that communication providers keep a log of their customers net browsing behaviour for a year.
    The National Highway Traffic Safety Administration NHTSA said in a letter to GM that it was permissible for the automaker to automatically activate hazard lights if a driver fails to respond to alerts by a vehicle that has brought itself to a stop but it raised concerns that the system is safe.
    GM monitoring system has facial recognition software that can detect if a driver is falling asleep or not paying attention spokesman Kevin Kelly said Monday.
    Concerns about vehicles that drive themselves for limited periods were raised after the May death of Ohio technology company owner Joshua Brown in a Tesla Motors Inc Model S while the car Autopilot system was engaged.
    Well I do not need to ask you because the government is passing a law about to finish its final stages in parliament that will force your internet service provider whether it be Virgin Media Sky or BT to keep that list for you.
    Would you then be surprised to hear that in parliament on Monday the chief executive of TalkTalk Dido Harding now a Conservative baroness and voted in favour of storing her own web histories so they could be handed over to the police on demand.
    Would you be equally surprised that while Diane Abbott the shadow home secretary said on Tuesday that the new law the investigatory powers bill was and that the legislation her Labour party colleagues in the House of Lords were voting with the Tory government against a Liberal Democrat amendment that would have stopped connection ICRs aka your web history being stored by the internet companies.
    Rudd the UK Home Secretary described the Investigatory Powers Bill as.
    She is right only in that it sets out one of the worst examples in the democratic world of government trampling on human rights online legalising the sweeping abuses under PRISM revealed by Edward Snowden.
    everything you do online can be spied on by a long list of government agencies will inevitably take away some of our precious freedom to use the web as a space for exploration and dissent.
    The feature is new to mobile devices though Twitter previously brought this design to the web in June.
    The new design also includes conversation counts so you can see which tweets are generating the most abuse and harassment at a glance.
    Twitter is a free app and you can download it on Android and iOS if you want.

 

PRE-MARKET | November 29, 2016 | $TSLA, $AAPL #trade, $GOLD, $USO, $CL_F, $JAZZ, $PFE, $REGN, $IBB

PRE-MARKET | November 29, 2016 | $TSLA, $AAPL #trade, $GOLD, $USO, $CL_F, $JAZZ, $PFE, $REGN, $IBB

PRE-MARKET MOVERS

 

UPGRADES

2. BAC:$BAC Upgrade DJ Bank of America Raised to Outperform From Market Perform by Keefe Bruyette & Woods Tue Nov 29 05:46:52 2016 EDT
4. PFE:$pfe upgraded to overweight by Barclays
5. TSCO:$TSCO gapping higher on zero volume on an upgrade from Northcoast , upgrading to BUY with a $102 price tgt
6. VCYT:$VCYT upgraded to Buy from Neutral at Janney

 

DOWNGRADES

11. SGEN:$SGEN downgraded to Equal-Weight from Overweight at Barclays
14. VRTX:$VRTX downgraded to Equal-Weight from Overweight at Barclays
15. WEN:$WEN downgraded to Neutral at Goldman Sachs
17. X:$X downgraded to Hold at Argus Research

 

EARNINGS

 

Trending Social Alerts

2. X:Good start to the day with $X down over $1.20,
3. TIF:Tiffany Q3 EPS $0.76, Revenue $949M vs $927M Est $TIF
4. MTSC:$MTSC Halted, news pending
8. CL_F:Crazy 80 cent drop in crude futures $CL_F
9. USO:iranian oil minister says will not cut production. $USO $CL_F

 

Trending News Headlines

1. CytRx CEO Pockets Millions of Dollars as Failed Sarcoma Drug Moves to FDA

CytRx announced a plan Tuesday to seek U.S. marketing approval of aldoxorubicin based more on hocus-pocus than credible science.

2. In OPEC Poker Game, Iran and Iraq Call Saudi Arabia’s Bluff

For decades, Saudi Arabia has had its way at OPEC. All of a sudden the position has turned: Riyadh finds its power waning against a resurgent Iran and Iraq.

3. Exclusive: ECB ready to buy more Italian bonds if referendum rocks market – sources

The European Central Bank is ready to temporarily step up purchases of Italian government bonds if the result of a crucial referendum on Sunday sharply drives up borrowing costs for the euro zone’s largest debtor, central bank sources told Reuters.

4. Don’t Be Surprised When Activision Blizzard CEO Does a Big Deal

Activision Blizzard Inc. is giving Chief Executive Officer Robert Kotick major financial incentives to do deals — a form of compensation that’s become increasingly unusual amid investor scrutiny.

5. Iran, Iraq at loggerheads with Saudis ahead of OPEC meeting

Iran and Iraq are resisting pressure from Saudi Arabia to curtail oil production, making it hard for the Organization of the Petroleum Exporting Countries to reach a global output-limiting deal when it meets on Wednesday.

6. Amazon Said to Plan Premium Alexa Speaker With Large Screen

Amazon.com Inc. is developing a premium Echo-like speaker with a screen, a sign the world’s largest online retailer is trying to capitalize on the surprise success of its voice-controlled home gadgets and fend off competition from Google and Apple Inc.

7. Jeweler Tiffany posts first sales rise in eight quarters

Tiffany & Co (TIF.N) reported its first rise in sales in eight quarters as strong sales in Japan and China more than offset a decline in the United States, its biggest market.

8. In OPEC’s High-Stakes Poker Game, Iran and Iraq Call Saudi Bluff

For decades, Saudi Arabia has had its way at OPEC. All of a sudden the position has turned: Riyadh finds its power waning against a resurgent Iran and Iraq.

9. Trillium Therapeutics Announces Conference Call and Webcast on December 5th to Discuss TTI-621 Data Presented at ASH

Trillium Therapeutics Inc. , a clinical stage immuno-oncology company developing innovative therapies for the treatment of cancer, today announced that it will host a conference call and webcast at 8:30 …

Technology News

    What that turned into was a state representative in the House in Colorado proposing actual legislation to prevent people from using their food stamps to buy marijuana based on something that had just never happened Coler says.
    It was just anybody with a blog can get on there and find a big huge Facebook group of kind of rabid Trump supporters just waiting to eat up this red meat that they about to get served Coler says.
    So it seems to be a kind of arbitrary step that they taking either based on I do know if it was my reputation within the industry or specifically the Denver Guardian site that angered them or I do know what it is but back to your question there hundreds of people that will work with me.
    ET CNN has acquired startup Beme a social media app launched last year by popular YouTube star Casey Neistat the network announced Monday.
    The Beme app which allowed users to shoot and share quick unedited video clips had an auspicious start thanks in large part to diehard social media following.
    The Beme app will be shuttered with the employees joining CNN to form a separate technology unit focusing on the new media venture and wider mobile video efforts.
    Tomorrow the White House will partner with Stanford University and the Chan Zuckerberg Initiative a limited liability corporation launched by the CEO of Facebook and his wife to the Summit on Poverty and Opportunity a event held on the campus.
    The list of attendees and speakers also includes CEO Steve Ballmer White House CTO Megan Smith formerly a top executive at Google Martin Ford author of two books on automation including Rise of the Robots Marian Edelman founder of the Defense Fund Nobel economist Ken Arrow and Bryan Desloge president of the National Association of Counties who backed Donald Trump in the presidential election and has participated in a previous White House summit on poverty.
    This event comes at a time when tech moguls like Mark Zuckerberg and Sean Parker have been subject to increased scrutiny for their approach to doing good which eschews nonprofit foundations for traditional investment vehicles labeled as philanthropy.
    CNN announced on Monday that it had agreed to acquire the technology and talent behind Beme the social media app built and started by Neistat and Matt Hackett a former vice president of engineering at Tumblr.
    Beme saw early traction especially among avid personal following but failed to capture a large part of the social sharing market amid competitors like Instagram Facebook and others.
    AMC the network known for the hit series Walking Dead announced this month that it had taken a minority stake in Funny or Die the digital comedy site founded by Will Ferrell and Adam McKay.
    What that turned into was a state representative in the House in Colorado proposing actual legislation to prevent people from using their food stamps to buy marijuana based on something that had just never happened Coler says.
    It was just anybody with a blog can get on there and find a big huge Facebook group of kind of rabid Trump supporters just waiting to eat up this red meat that they about to get served Coler says.
    So it seems to be a kind of arbitrary step that they taking either based on I do know if it was my reputation within the industry or specifically the Denver Guardian site that angered them or I do know what it is but back to your question there hundreds of people that will work with me.
    At an event in New York City today AT T has announced that its mobile subscribers will be able to stream its new DirecTV Now service without using their data.
    AT T is just the latest to challenge the ruling but with a new and likely more lenient administration at least on net neutrality the bet to go against the FCC may just pay off.
    DirecTV Now will be available on November and will offer over channels starting at a month for a limited time.
    The incident is one of several examples including threats of regulation and attempts to prosecute chief executive Mark Zuckerberg of how Germany has become an important test case globally for how the social network polices what may be published online and how it should respond to inappropriate and illegal content.
    a mural by Günther Schaefer that depicts a Star of David on a German flag is painted on the remains of the Berlin Phil Moore for The New York Times recognize that this is a work in progress Richard Allen director of policy in Europe said in an interview.
    Jun recently filed a complaint with Munich authorities seeking prosecution of Zuckerberg and other senior Facebook executives on charges they failed to sufficiently tackle the widespread wave of hate speech in Germany.
    At an event in New York City today AT T has announced that its mobile subscribers will be able to stream its new DirecTV Now service without using their data.
    AT T is just the latest to challenge the ruling but with a new and likely more lenient administration at least on net neutrality the bet to go against the FCC may just pay off.
    DirecTV Now will be available on November and will offer over channels starting at a month for a limited time.
    Tomorrow the White House will partner with Stanford University and the Chan Zuckerberg Initiative a limited liability corporation launched by the CEO of Facebook and his wife to the Summit on Poverty and Opportunity a event held on the campus.
    The list of attendees and speakers also includes CEO Steve Ballmer White House CTO Megan Smith formerly a top executive at Google Martin Ford author of two books on automation including Rise of the Robots Marian Edelman founder of the Defense Fund Nobel economist Ken Arrow and Bryan Desloge president of the National Association of Counties who backed Donald Trump in the presidential election and has participated in a previous White House summit on poverty.
    This event comes at a time when tech moguls like Mark Zuckerberg and Sean Parker have been subject to increased scrutiny for their approach to doing good which eschews nonprofit foundations for traditional investment vehicles labeled as philanthropy.
    In April of this year Steve Hill executive director of the Nevada Office of Economic Development GOED wrote an email to Jude Hurin the administrator in charge of autonomous vehicle AV regulation at the DMV.
    Otto had now come full circle from a tiny startup intent on disrupting taxis in Las Vegas to maverick autonomous truckers to a key part of the biggest company on the planet.
    The testing facility a wholly owned subsidiary called Nevada ATCF LLC received its license from the DMV at the end of September and is currently hiring staff and remodeling a building in southwest Las Vegas.

 

PRE-MARKET | November 23, 2016 | $BIIB, $NFLX, $CL_F, $GDX, $GLD, $SLV, $ES_F, $JUNO, $AMZN, $NFLX, $AAPL

PRE-MARKET | November 23, 2016 | $BIIB, $NFLX, $CL_F, $GDX, $GLD, $SLV, $ES_F, $JUNO, $AMZN, $NFLX, $AAPL

PRE-MARKET MOVERS

 

UPGRADES

 

DOWNGRADES

 

EARNINGS

 

Trending Social Alerts
1. LLY:$LLY Solanezumab fails
2. IBB:If U trade actively you need to notice small changes. $ibb did show relative weakness yesterday. Someone always kno…
3. JUNO:$JUNO clinical hold on jcar15
4. AXON:$LLY ↓ 15%, $BIIB ↓ 9%, $AXON ↓ 18% PM
5. ESEA:$ESEA *DJ Euroseas: To Buy Panamax Size Drybulk Carrier for Approximately $4.4 Million >ESEA
6. DE:Deere Q4 earnings: EPS $0.90 Revenue $5.65bln $DE
9. CLRB:$CLRB raises $8m at $1.50, warrants also
10. GDX:@TheTradingNinja $gdx 19.00 Dec 16th puts had bought 3 a week ago Just saw gold now below 1200 $$$$$$$$$$$$$$$$$$$$$$$$$$
11. BIIB:$LLY down 10% pre-market, $BIIB down 4.6% on solanezumab phase 3 failure

 

Trending News Headlines
1. Juno Therapeutics Places JCAR015 Phase II ROCKET Trial on Clinical Hold

Juno Therapeutics, Inc. , a biopharmaceutical company focused on re-engaging the body’s immune system to revolutionize the treatment of cancer, today announced that it has voluntarily placed on hold the Phase II clinical trial of JCAR015 in adult patients with relapsed or refractory B cell acute lymphoblastic

2. Juno Therapeutics CAR-T Study Halts Following Another Additional Patient Death

Juno Therapeutics halted a clinical trial involving its most advanced CAR-T therapy for the second time in five months after another two cancer patients developing brain swelling.

3. Exclusive: ECB seeks to lend out more bonds to avert market freeze – sources

The European Central Bank is looking for ways to lend out more of its huge pile of government debt to avert a freeze in the 5.5 trillion-euro short-term funding market that underpins the financial system, central bank sources told Reuters.

4. Meg Tirrell on Twitter

“$JUNO halts ROCKET trial after two patients get cerebral edema; one died, other expected not to recover”

5. Bio Stocks™ on Twitter

“$LLY ↓ 15%, $BIIB ↓ 9%, $AXON ↓ 18% PM”

6. Eli Lilly’s Alzheimer’s drug fails key clinical trial

Based on the negative study results, Lilly will not pursue regulatory approvals for solanezumab in Alzheimer’s disease.

7. Facebook Said to Create Censorship Tool to Get Back Into China

The social network, blocked in China since 2009, has developed software to keep posts from appearing in users’ news feeds in specific geographic areas, current and former employees said.

8. Eli Lilly and Co – LLY – Stock Quotes

Eli Lilly and Co, LLY real time stock quotes, news, videos at CNBC.com

9. Lilly Announces Top-Line Results of Solanezumab Phase 3 Clinical Trial (NYSE:LLY)

/* Style Definitions */ span.prnews_span { font-size:8pt; font-family:”Arial”; color:black; } a.prnews_a { color:blue; } li.prnews_li { font-size:8pt; font-family:”Arial”; color:black; } p.prnews_p { font-size:0.62em; font-family:”Arial”; color:black; margin:0in; }

10. Lilly Announces Top-Line Results of Solanezumab Phase 3 Clinical Trial

INDIANAPOLIS, Nov. 23, 2016 /PRNewswire/ — Eli Lilly and Company (LLY) today announced that solanezumab did not meet the primary endpoint in the EXPEDITION3 clinical trial, a phase 3 study of solanezumab in people with mild dementia due to Alzheimer’s disease (AD). Patients treated with solanezumab

11. One dead, one dying as Juno’s lead CAR-T turns lethal again; trial halted

Juno’s lead CAR-T drug is killing more patients. Four months after the biotech was forced to scramble to save the program in the wake of three patient deaths, Juno says that one more patient has died of cerebral edema and another is at death’s door. Juno has voluntarily put the

12. Eli Lilly’s Late-Stage Alzheimer’s Trial Fails to Achieve Goal

Eli Lilly’s shares plunge as a closely watched late-stage trial of an Alzheimer’s drug had failed to achieve its goal.

13. Deere Jumps as Profit Forecast Beats Estimates Amid Cost Cuts

Deere & Co. posted quarterly earnings and a 2017 profit forecast that exceeded analysts’ estimates as the world’s largest agricultural equipment maker’s cost-cutting efforts offset some of the effects of lower demand. The shares rose as much as 13 percent in pre-market trading.

14. Shane Blackmon on Twitter

“$JUNO clinicla hold on Phase 2 Rocket Trial”

15. Trump chooses Governor Nikki Haley for U.N. ambassador: news reports

President-elect Donald Trump has chosen South Carolina Governor Nikki Haley, a daughter of immigrants from India who has little international experience, to be U.S. ambassador to the United Nations, The Post and Courier newspaper and other media reported on Wednesday.

Technology News
    Devorah Heitner author of and founder of Raising Digital Natives an Evanston provider of consulting services to schools suggests parents pick up on their interests and help them to find and evaluate news on the topic online.
    Many students multitask by texting reading and watching video at once hampering the concentration needed to question content and think deeply says Yalda Uhls a research psychologist at the Digital Media Center at the University of California Los Angeles.
    Talk with teens about information found online and ask did you click on that says Will Colglazier a history teacher at Aragon High School in San Mateo who is helping test Stanford University teaching materials aimed at remedying the problem.
    Devorah Heitner author of and founder of Raising Digital Natives an Evanston provider of consulting services to schools suggests parents pick up on their interests and help them to find and evaluate news on the topic online.
    Many students multitask by texting reading and watching video at once hampering the concentration needed to question content and think deeply says Yalda Uhls a research psychologist at the Digital Media Center at the University of California Los Angeles.
    Talk with teens about information found online and ask did you click on that says Will Colglazier a history teacher at Aragon High School in San Mateo who is helping test Stanford University teaching materials aimed at remedying the problem.
    The social network has quietly developed software to suppress posts from appearing in news feeds in specific geographic areas according to three current and former Facebook employees who asked for anonymity because the tool is confidential.
    Instead it would offer the software to enable a third party in this case most likely a partner Chinese company to monitor popular stories and topics that bubble up as users share them across the social network the people said.
    More broadly China has streamlined and tightened its controls over the internet under President Xi targeting influential social media celebrities and adding new reviews to popular online video sites.
    When it comes to evaluating information that flows across social channels or pops up in a Google search young and otherwise students can easily be duped finds a new report from researchers at Stanford Graduate School of Education.
    At the high school level one assessment tested whether students were familiar with key social media conventions including the blue checkmark that indicates an account was verified as legitimate by Twitter and Facebook.
    The researchers found that high production values links to reputable news organizations and polished pages had the ability to sway students into believing without very much skepticism the contents of the site.
    If ever answered questions like these on one of the free personality quizzes floating around Facebook have learned known as your Ocean score How you rate according to the big five psychological traits of Openness Conscientiousness Extraversion Agreeableness and Neuroticism.
    Cambridge is reportedly backed by Robert Mercer a hedge fund billionaire and a major Republican donor a key board member is Stephen Bannon the head of Breitbart News who became campaign chairman and is set to be his chief strategist in the White House.
    Ever since the advertising executive Lester Wunderman coined the term in the ability to target specific consumers with ads rather than blanketing the airwaves with mass appeals and hoping the right people will hear them has been the holy grail.
    AppNexus operator of one of the biggest digital advertising services has barred Breitbart News from using its tools because the conservative online publisher violated its hate speech rules.
    Breitbart News Network continues to experience exceptional growth having attracted over million unique visitors in the last thirty days alone Solov also said in his statement.
    The online publication has been criticized for incendiary articles such as one that warns of Muslim invaders and another that dubs conservative thinker Bill Kristol a Renegade Jew.
    If ever answered questions like these on one of the free personality quizzes floating around Facebook have learned known as your Ocean score How you rate according to the big five psychological traits of Openness Conscientiousness Extraversion Agreeableness and Neuroticism.
    Cambridge is reportedly backed by Robert Mercer a hedge fund billionaire and a major Republican donor a key board member is Stephen Bannon the head of Breitbart News who became campaign chairman and is set to be his chief strategist in the White House.
    Ever since the advertising executive Lester Wunderman coined the term in the ability to target specific consumers with ads rather than blanketing the airwaves with mass appeals and hoping the right people will hear them has been the holy grail.
    Two years ago Ben Kaufman of consumer product startup Quirky delivered one of the most awkward and candid interviews ever witnessed at annual Brainstorm Tech conference.
    Before it created BuzzFeed Product Lab commerce efforts revolved around affiliate links where the media company gets paid for driving sales to third party sites.
    Now BuzzFeed is chasing the holy grail of commerce an area that has eluded social platforms like Facebook for years and killed many other startups tackling the category along the way.
    Nathaniel Faggioli the company chief operating officer a former Goldman Sachs banker has pushed his employees to find ways to improve its margins as the startup tries to attract another round of financing according to the people.
    Meanwhile Munchery line cooks in San Francisco its flagship market stayed up until assembling Vietnamese caramel chicken roasted half game hen and beef pho said the current and former employees.
    From September to July Munchery San Francisco kitchen made about dishes an entree or a side that never got sold according to an internal financial document and interviews with who asked to remain anonymous out of fear of reprisal from their former employer.
    The social network has quietly developed software to suppress posts from appearing in news feeds in specific geographic areas according to three current and former Facebook employees who asked for anonymity because the tool is confidential.
    Instead it would offer the software to enable a third party in this case most likely a partner Chinese company to monitor popular stories and topics that bubble up as users share them across the social network the people said.
    More broadly China has streamlined and tightened its controls over the internet under President Xi targeting influential social media celebrities and adding new reviews to popular online video sites.

 

PRE-MARKET | November 22, 2016 | $SPX, $CL_F, $DLTR, #OPTIONS, $SINA, $AAPL, $SNY, $GE, $FB

PRE-MARKET | November 22, 2016 | $SPX, $CL_F, $DLTR, #OPTIONS, $SINA, $AAPL, $SNY, $GE, $FB

PRE-MARKET MOVERS

 

UPGRADES

 

DOWNGRADES

14. LOCK:$LOCK downgraded to Hold at Deutsche Bank – PT $24, downgraded to Hold at Canaccord Genuity – PT raise $24 from $23

 

EARNINGS

 

Trending Social Alerts

1. MDT:After a big year outperforming #biotech, #Medtech falling apart after Q3 earnings… $MDT $EW $DXCM etc
3. TGTX:$TGTX Announces Positive DSMB Recommendation for Continuation of the UNITY-CLL Phase 3 Trial
5. QURE:$QURE Updated Clinical Data on AMT-060 in Hemophilia B at #ASH16
6. ADI:Analog Devices Reports Q4 EPS $1.05 vs. Est. $0.89, Rev. $1B vs. Est. $942M $ADI

 

Trending News Headlines

1. Nearly 350 Abstracts Evaluating Celgene Therapies to Be Presented at American Society of Hematology Annual Meeting (ASH) | Business Wire

Celgene Corporation (NASDAQ:CELG) today announced that data from nearly 350 abstracts, including more than 150 oral presentations, evaluating Celgene

2. AIG joins list of finance companies looking to move from Britain

U.S. insurer AIG (AIG.N) may move its European headquarters from London to another European Union country because of Britain’s vote to leave the EU, the head of the AIG’s European and UK operations said at an industry conference on Tuesday.

3. Trump cancels meeting with New York Times, complaining about ‘nasty tone’

President-elect Donald Trump abruptly canceled a meeting scheduled for Tuesday with The New York Times newspaper that he has frequently criticized, complaining in morning Twitter posts about inaccurate coverage and a “nasty tone.”

4. Early movers: CPB, DPS, KKR, MDT, DSW, PANW, BA, JACK, AZN & more

Some of the names on the move ahead of the open.

5. Dollar Tree is climbing after strong earnings and guidance

The stock is climbing after better than expected results.

6. Dr Pepper Snapple to Acquire Bai Beverages for $1.7 Billion

Dr Pepper Snapple Group agreed to buy Bai Brands, the maker of low-calorie, coffee-fruit drinks, for $1.7 billion, as consumers continue to turn away from traditional sodas.

7. Iteris to Attend the Benchmark Discovery Conference in Chicago on December 1, 2016 | Business Wire

Iteris’ CEO, Joe Bergera, and CFO, Andy Schmidt, will be participating in the Benchmark Annual Micro Cap Discovery Conference taking place on December

8. OPEC experts resume talks on oil output cut, delegates upbeat

OPEC experts discussing how to implement a plan to cut oil output are likely to reach agreement later on Tuesday, a Nigerian delegate said, a possible sign of progress in finalizing the group’s first supply-limiting deal since 2008.

Technology News

    Just imagine what things will look like if the unsavory elements that tore through the election false narratives fake news and aggressive efforts to delegitimize traditional journalism come back into play as Donald Trump presses to enact his agenda.
    The national security adviser Trump named last week Michael Flynn a retired Army lieutenant general has subscribed to the conspiracy theory that Shariah law is taking root in the United States it contributing to his insistence that Americans have every reason to view Islam as.
    not so outlandish to envision attempts to sell his plans getting a lift from the likes of Jones or a fake site out of Macedonia perhaps claiming that Democrats are working with ISIS to use undocumented immigrants to poison local water supplies or some such.
    It made a huge push over the last four years to be a destination for news indeed to be your personalized Since that Obama tweet the company retooled its platform creating a system designed to make it easier to share and promote timely and trending stories and to help them spread rapidly across its network.
    On June Donald Trump hit the ground in Iowa and began campaigning for president taking shots at his fellow Republican contenders and telling the news media that only he could beat Democratic frontrunner Hillary Clinton.
    With the presidential primaries underway another fundamental change was taking place inside Facebook one responsible for giving even more prominence to posts from news organizations and public figures though the company had not yet started reckoning with it.
    It made a huge push over the last four years to be a destination for news indeed to be your personalized Since that Obama tweet the company retooled its platform creating a system designed to make it easier to share and promote timely and trending stories and to help them spread rapidly across its network.
    On June Donald Trump hit the ground in Iowa and began campaigning for president taking shots at his fellow Republican contenders and telling the news media that only he could beat Democratic frontrunner Hillary Clinton.
    With the presidential primaries underway another fundamental change was taking place inside Facebook one responsible for giving even more prominence to posts from news organizations and public figures though the company had not yet started reckoning with it.
    Nathaniel Faggioli the company chief operating officer a former Goldman Sachs banker has pushed his employees to find ways to improve its margins as the startup tries to attract another round of financing according to the people.
    Meanwhile Munchery line cooks in San Francisco its flagship market stayed up until assembling Vietnamese caramel chicken roasted half game hen and beef pho said the current and former employees.
    From September to July Munchery San Francisco kitchen made about dishes an entree or a side that never got sold according to an internal financial document and interviews with who asked to remain anonymous out of fear of reprisal from their former employer.
    were happy with the successful first test flight and were able to verify several performance models and components including aerodynamics batteries control systems and crew training with no major unexpected results the company said in an statement.
    Company Chief Executive Officer Mark Zuckerberg said he was deeply disappointed when a SpaceX rocket explosion destroyed a Facebook satellite that would have helped spread internet access across Africa.
    Indonesian Vice President Jusuf Kalla spoke to Zuckerberg in recent days at the Economic Cooperation summit in Peru about using the Aquila drone to beam internet to remote parts of the country the Jakarta Post reported.
    As John Herrman argued in a recent New York Times article part of the difficulty in solving the problem stems from the fact that many people appear to have lost faith in the existing media.
    This is part of the reason why the problem be solved by appointing an for Facebook as Washington Post media writer and former New York Times public editor Margaret Sullivan recommended in a recent column.
    Take a look at the recent analysis by the New York Times of a single fake news story A man in Texas posts a photo of a bus on Twitter and says he thinks it is carrying paid protesters to an rally.
    is exploring an ambitious push to infiltrate the last bastion of traditional live sports.
    In recent months the giant has been in talks with heavy hitters like the National Basketball Association Major League Baseball and the National Football League for the rights to carry live games according to people familiar with the matter.
    It also has talked with soccer lacrosse and surfing.
    The news comes hours after it was revealed that Goldman Sachs one of the original members of the consortium effort would depart the group.
    A source close to the deal indicates that Santander is among a small number of firms that may have privately withdrawn from the consortium in recent weeks and that a planned funding round is still moving ahead.
    Developing technology like this requires dedication and significant resources and our diverse pool of members all have different capacities and capabilities which naturally change over time.
    Nathaniel Faggioli the company chief operating officer a former Goldman Sachs banker has pushed his employees to find ways to improve its margins as the startup tries to attract another round of financing according to the people.
    Meanwhile Munchery line cooks in San Francisco its flagship market stayed up until assembling Vietnamese caramel chicken roasted half game hen and beef pho said the current and former employees.
    From September to July Munchery San Francisco kitchen made about dishes an entree or a side that never got sold according to an internal financial document and interviews with who asked to remain anonymous out of fear of reprisal from their former employer.
    It made a huge push over the last four years to be a destination for news indeed to be your personalized Since that Obama tweet the company retooled its platform creating a system designed to make it easier to share and promote timely and trending stories and to help them spread rapidly across its network.
    On June Donald Trump hit the ground in Iowa and began campaigning for president taking shots at his fellow Republican contenders and telling the news media that only he could beat Democratic frontrunner Hillary Clinton.
    With the presidential primaries underway another fundamental change was taking place inside Facebook one responsible for giving even more prominence to posts from news organizations and public figures though the company had not yet started reckoning with it.

 

PRE-MARKET | November 21, 2016 | $GEN, $CL_F, $USO, $MLNX, $MPEL, $WYNN, $MGM, $FOSL

PRE-MARKET | November 21, 2016 | $GEN, $CL_F, $USO, $MLNX, $MPEL, $WYNN, $MGM, $FOSL

UPGRADES

3. FOSL:$FOSL upgraded to Neutral at Piper Jaffray

 

DOWNGRADES

1. CEMP:$CEMP downgraded to Market Perform at Cowen, PT removed.

 

EARNINGS

 

Trending Social Alerts
1. HALO:$HALO today announced that AbbVie has discontinued a development program using the Halozyme ENHANZE™ platform technology
2. DRYS:$DRYS *DJ DryShips’s Lending Bank Has Agreed to a Write-Off of Approximately 50% of the Outstanding Principal and Interest Due >DRYS
6. TSN:#BREAKING: Tyson Foods $TSN Q4 Adjusted Earnings Per Share misses estimates, $0.96 vs. $1.17 expected
7. ADRO:$ADRO Partial Clinical Hold Lifted and Enrollment Resumes for Aduro Biotech LADD Clinical Trials

 

Trending News Headlines
1. Apple Abandons Development of Wireless Routers

Apple Inc. has disbanded its division that develops wireless routers, another move to try to sharpen the company’s focus on consumer products that generate the bulk of its revenue, according to people familiar with the matter.

Technology News
    NPR decided to the system by flagging nearly posts that could be considered hate speech specifically attacks against blacks and against whites in the We found that Facebook subcontractors were not consistent and made numerous mistakes including in instances where a user calls for violence.
    We say they were mistakes because the company changed its position in dozens of instances removing some and restoring others either when we flagged it a second time through the automated system or brought it to the attention of Facebook headquarters in Menlo Park Calif.
    Some in Silicon Valley dismiss the criticisms against Facebook as schadenfreude Just like taxi drivers do like Uber legacy media envies the success of the social platform and enjoys seeing its leadership on the hot seat.
    terrorists into encrypted channels however impedes their operational effectiveness by constraining the amount of data they can send and complicating transmission protocols a phenomenon known in military parlance as virtual attrition Pompeo wrote in an published in January by The Wall Street Journal.
    of us believe that a couple of years in the Army followed by sitting on a committee in Congress qualifies anyone for any position in the CIA much less as the Director a former military officer who also worked in the intelligence community told Motherboard on condition of anonymity.
    believe that the ongoing nepotism used to select unqualified and in some cases dangerous people for leadership in these key positions may well lead to a catastrophic failure for the United.
    Khizr Khan the father of an American soldier killed in Iraq and a critic of Donald Trump was smeared in articles on Images Something is deeply wrong when the voice reputation and influence can be borrowed by a source that describes itself as fantasy news to claim that he has endorsed a presidential candidate and then be amplified unchallenged through a million individual shares.
    But the outrage is at risk of being misdirected and will be followed by the realization that the colloquial the newslike media amateur and professional for which truth is defined first in personal and political terms and which must only meet the bar of not being obviously inarguably demonstrably false will continue growing apace gaining authority by sheer force not despite Facebook but because of it.
    Those who expect the operator of the dominant media ecosystem of our time in response to getting caught promoting lies to suddenly return authority to the companies it has superseded are in for a similar surprise.
    CloseCloseCloseCountryCodeFor customers ofUnited any any United Orange Airtel Videocon Telkomsel Indosat XL See SMS short codes for other countries.
    This timeline is where spend most of your time getting instant updates about what matters to you.
    Hover over the profile pic and click the Following button to unfollow any account.
    terrorists into encrypted channels however impedes their operational effectiveness by constraining the amount of data they can send and complicating transmission protocols a phenomenon known in military parlance as virtual attrition Pompeo wrote in an published in January by The Wall Street Journal.
    of us believe that a couple of years in the Army followed by sitting on a committee in Congress qualifies anyone for any position in the CIA much less as the Director a former military officer who also worked in the intelligence community told Motherboard on condition of anonymity.
    believe that the ongoing nepotism used to select unqualified and in some cases dangerous people for leadership in these key positions may well lead to a catastrophic failure for the United.
    The June Intelligent Oven uses a combination of its camera scale touchscreen ports apps and continuously updated cooking presets to make you the best possible meal.
    The June oven uses carbon fiber heating elements that can fully power up in three seconds which greatly reduces the time needed for preheat.
    I do however think this lack of crust and visual appeal is fixable if June tests heat at the beginning or end of their meat presets as part of getting the inside up to temp.
    Please systematize this Give trusted media sources and agencies a path to report their findings so that Facebook and other social platforms can surface this information to users when they read these items and more importantly as they consider sharing them.
    Or is that deeper information better revealed by getting quicker to the next listing in the search results Wikipedia explaining that Daily Stormer is an American and white supremacist news and commentary website.
    Love or hate Occupy Democrats racked up to million impressions a week on Facebook according to its cofounder by providing users with the social tokens to use in their own conversations the thing they share because it speaks for them.
    Alarmed by the statistics the Department of Transportation in October outlined a plan to work with the National Safety Council and other advocacy groups to devise a to strategy with the ambitious goal of eliminating roadway fatalities within years.
    whole principle is to bring voice recognition to customers so they can keep their eyes on the road and hands on the wheel said Alan Hall a spokesman for Ford which began installing Sync in cars in.
    William Chandler a retired neurosurgeon in Ann Arbor just bought a BMW sport utility vehicle that warns him if he drifts out of his lane on the highway or if a car is in his blind spot.
    Now the firm has its next bet Marco Polo a small video messaging app run by a company called Joya Communications.
    The app seems pretty simple users can send each other short video messages with text or filters added on.
    As Snapchat has become more and more public with features like Discover and Stories investors are looking for products that might be able to use the same video messaging idea in a more intimate way.
    Alarmed by the statistics the Department of Transportation in October outlined a plan to work with the National Safety Council and other advocacy groups to devise a to strategy with the ambitious goal of eliminating roadway fatalities within years.
    whole principle is to bring voice recognition to customers so they can keep their eyes on the road and hands on the wheel said Alan Hall a spokesman for Ford which began installing Sync in cars in.
    William Chandler a retired neurosurgeon in Ann Arbor just bought a BMW sport utility vehicle that warns him if he drifts out of his lane on the highway or if a car is in his blind spot.