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1. BIIB:$BIIB Final Phase 3 Study Data Show SPINRAZA Significantly Improved Motor Function in Children With Later-Onset Spinal Muscular Atrophy
2. BCR:BAML sees $BCR / $BDX deal very bullish for Med-Tech, expects more mega deals over next 12-24 months, 5th large cap consolidation in 3 yrs

 

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1. Akari Therapeutics Demonstrates Positive Response with Coversin in Ongoing Phase 2 PNH Trial and in Additional Clinical Targets

-Interim Phase 2 PNH data demonstrate positive response with Coversin™ -Phase 3 PNH program expected to commence in 4Q2017 -Data from preclinical aHUS model demonstrates positive results -New preclinical data demonstrates positive response of Coversin’s combined C5 and LTB4 therapy in skin and eye models -Phase 2 programs in Mucous Membrane Pemphigoid (eye) and Bullous Pemphigoid (Skin) expected to commence in 1Q2018

2. Biogen Hopes New Spine Drug Data Convinces Insurers to Loosen Patient Access, Boosts Sales

When Biogen reports first-quarter earnings Tuesday, investors will be looking to see if Spinraza sales match or exceed $16 million consensus.

3. Cara Therapeutics Announces Positive Data From Quantitative Phase 1 Trial Measuring Respiratory Safety of I.V. CR845

– I.V. CR845 statistically equivalent to placebo across all measures of respiratory safety –

Technology News
    Taxi drivers and others who supported de efforts to halt expansion rallying outside City Hall in Manhattan in Hiroko New York Times In some places Uber employees were also told to create computer programs known as scripts that would automatically vote for the service in surveys.
    Kalanick and a top lieutenant Emil Michael sometimes hung out with Leonardo DiCaprio who is also an investor and Jay Z whose wife Beyoncé performed for Uber employees at a poolside party in Las Vegas in.
    And just days after a former employee published a blog post in February detailing sexual harassment at Uber Kalanick attended Vanity Academy Awards party in Hollywood stunning some colleagues with his perceived insensitivity.
    But for every streamer that achieves partnership there are thousands more striving toward that goal many of them sharing amazing content with strong passionate communities but without access to tools that would allow their viewers to help support them.
    While Affiliates will eventually have access to basic versions of our tools including Subscriptions Game Commerce and Advertising we will continue developing additional features just for Partners that are tailored for nurturing the larger communities they manage.
    When we launch qualified streamers will be notified via email Notification and an announcement in the upper left corner of your dashboard.
    Minutes later they took the hacker away into custody a subdued end to an international cyber drama that involved the highest levels of the US government Russian spies a global cybercrime syndicate and hundreds of millions of unsuspecting Americans.
    Once the group had gained access to Yahoo its targets included an economic development minister of a country bordering Russia an investigative reporter who worked for Russian newspaper Kommersant and a managing director of a US private equity firm court documents show.
    Ruslan Stoyanov the former head of cybercrime investigations at Kaspersky Lab a cybersecurity company recently went public with claims that the Russian government systematically recruits hackers from the criminal underground and gives them immunity in exchange for their services in a letter published by the independent television station Dozhd.
    In a Booz Allen report commissioned by the Immigration and Naturalization Services highlighted a worrying trend employers were taking advantage of loose regulation to replace domestic workers with cheaper imported labor in entry level positions.
    In January Microsoft said in a regulatory filing that immigration policy changes or restrictions inhibit our ability to adequately staff our research and development That month Silicon Valley was fretting over the direction of the debate on visas companies like Infosys and Tata took a massive hit on their stock prices.
    On a call with reporters this week to introduce a new executive order Trump administration officials directly criticized outsourcing companies for their use of visas saying their strategies are from how the program is generally pictured.
    Minutes later they took the hacker away into custody a subdued end to an international cyber drama that involved the highest levels of the US government Russian spies a global cybercrime syndicate and hundreds of millions of unsuspecting Americans.
    Once the group had gained access to Yahoo its targets included an economic development minister of a country bordering Russia an investigative reporter who worked for Russian newspaper Kommersant and a managing director of a US private equity firm court documents show.
    Ruslan Stoyanov the former head of cybercrime investigations at Kaspersky Lab a cybersecurity company recently went public with claims that the Russian government systematically recruits hackers from the criminal underground and gives them immunity in exchange for their services in a letter published by the independent television station Dozhd.
    Many of the people interviewed for this article who revealed previously unreported details of life asked to remain anonymous because they had signed nondisclosure agreements with Uber or feared damaging their relationship with the chief executive.
    When the company struggled Kalanick and a partner took the tax dollars from employee paychecks which are supposed to be withheld and sent to the Internal Revenue Service and reinvested the money into the even as friends and advisers warned him the action was potentially illegal.
    Travis Kalanick I came to know years ago was relentless in pursuit of his goals at the expense of those who supported him along the way deluded by his own embellished personal narrative and a serial prevaricator said Peter Yorke a former Red Swoosh adviser and a longtime tech executive.
    Taxi drivers and others who supported de efforts to halt expansion rallying outside City Hall in Manhattan in Hiroko New York Times In some places Uber employees were also told to create computer programs known as scripts that would automatically vote for the service in surveys.
    Kalanick and a top lieutenant Emil Michael sometimes hung out with Leonardo DiCaprio who is also an investor and Jay Z whose wife Beyoncé performed for Uber employees at a poolside party in Las Vegas in.
    And just days after a former employee published a blog post in February detailing sexual harassment at Uber Kalanick attended Vanity Academy Awards party in Hollywood stunning some colleagues with his perceived insensitivity.
    On anonymous online forums raters swap instance looking up rap video lyrics to scan quickly for profanity or skipping through a clip in chunks instead of watching the entire thing.
    But while only machine intelligence can grapple with scale as company execs and representatives have stressed again and again until anyone smart enough to distinguish say truly offensive speech from other forms of expression on its own such efforts will still need to rely on people.
    Big companies across the tech industry employ temporary workers to participate in repetitive tasks meant to train AI systems according to multiple ad raters WIRED spoke with.
    Sure we have a Terms of Service Agreement and a Privacy Policy that our users agree they have read and understand before they even sign up but the reality is most of us myself included do take the time to thoroughly review them.
    So we need to do better for our users and will from this point forward with clearer messaging on our website in our app and in our FAQs.
    The rest will remain the same providing a killer service that gives you hours back in your day while protecting your privacy and security above all else.
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