PRE-MARKET MOVERS

 

UPGRADES

2. CHK:$CHK – upgraded to Hold at Jefferies
10. NOC:$NOC upgraded to Overweight at Barclays – PT raise $270 from $230
12. PCLN:$PCLN upgraded to Buy at Stifel Nicolaus – PT raise $1.9k from $1.65

 

DOWNGRADES

8. MS, VRX:Rodman downgrades $vrx to neutral. $ms cuts PT from $42 to $25.
11. VRX:$VRX downgraded to Neutral at Rodman & Renshaw – PT cut $23 from $81, maintains Overweight rating at Morgan Stanley – PT cut $25 from $42

 

EARNINGS

 

Trending Social Alerts

2. ANTH:$ANTH Blisibimod CHABLIS-SC1 Phase 3 Study Did Not Achieve the Primary Endpoint in Patients With Active Systemic Lupus Erythematosus #Fail
4. IBB:$XBI up 2.7% $IBB up 1.93% in pm
5. SODA:$SODA Reports Q3 EPS $0.69 vs. Est. $0.23, Rev. $124.2M vs. Est. $115M – double digit growth 🙂
6. SGEN:$SGEN Receives FDA Breakthrough Therapy Designation for ADCETRIS® in Mycosis Fungoides & Primary Cutaneous Anaplastic Large Cell Lymphoma
7. MNKD:.@AdamSinger Neither do I, but it’s a bizarre announcement. Does $MNKD have compromising photos or similar?
8. CELG:@tgtxdough $IBB $CELG coiled spring of money flow may need to shift back over to biotech.
9. KSS:Kohl’s Reports Q3 Adj. EPS $0.80 vs $0.70 Est., Sales $4.327B vs $4.33B Est. $KSS
11. TUBE:$TUBE Adobe $ADBE to acquire TubeMogul for $14/sh

 

Trending News Headlines

1. Six thoughts on President Trump and the durability of the biotech stock rally

Investors have convinced themselves that President Donald Trump is going to make drug stocks great again. Will it last?

2. Bristol-Myers hands over $100M in cash for a new fibrosis drug, beefing up NASH focus

It’s not all checkpoints all the time at Bristol-Myers Squibb. The big biotech has been ramping up an ambitious effort in fibrosis and NASH and this morning it’s taking the wraps off another deal in the field, paying $100 million to Japan’s Nitto Denko for an early-stage drug candidate that

3. Opdivo (nivolumab) Demonstrates Overall Survival Benefit in Patients With Unresectable Advanced or Recurrent Gastric Cancer in Phase 3 Study

Opdivo is the first and only Immuno-Oncology agent to demonstrate overall survival advantage in patients with unresectable advanced or recurrent gastric cancer refractory to, or intolerant of, standard therapy Bristol-Myers Squibb Company (NYSE:BMY) announced today that ONO-4538-12, a Phase 3, randomized, double-blind clinical trial evaluating the efficacy and safety of Opdivo (nivolumab) in patients with unresectable advanced or recurrent gastric cancer refractory to, or intolerant of, standard therapy, met its primary endpoint of overall survival (OS). Ono Pharmaceutical Co. Ltd. of Japan , Bristol-Myers Squibb’s development partner for Opdivo , conducted the ONO-4538-12 trial. The companies will work with investigators on the future presentation of the study results. Fouad Namouni, M.D., head of development, Oncology, Bristol-Myers Squibb, commented, “Patients with advanced or recurrent gastric cancer generally have a poor prognosis, and there are currently no standard-of-care

4. Halozyme Announces Broad Clinical Collaboration Agreement To Evaluate PEGPH20 And Tecentriq In Up To Eight Tumor Types

Phase 1b/2 studies will evaluate Halozyme’s investigational drug, PEGPH20 with Genentech’s anti-PDL1 Tecentriq® (atezolizumab) Halozyme Therapeutics, Inc. (NASDAQ: HALO), an oncology biotech developing novel oncology and drug-delivery therapies, and Genentech, a member of the Roche Group , today announced an agreement to collaborate on clinical studies evaluating up to eight different tumor types beginning in 2017. The first study will be a Phase 1b/2 open-label, multi-arm randomized global study, led by Genentech to evaluate their cancer immunotherapy Tecentriq® (atezolizumab), an anti-PD-L1 monoclonal antibody, in combination with Halozyme’s investigational drug, PEGPH20 in six tumor types. Halozyme will supply drug only for the Genentech study. This study will have an initial focus on gastrointestinal malignancies, including pancreatic and gastric cancers. The second study will be a Phase 1b open-label randomized study led by Halozyme to assess Tecentriq in combination with PEGPH20

5. Andy Biotech on Twitter

“$AZN discontinues its Anti-CD19 in DLBCL and Anti-ANG2 in solid tumors. $JUNO $KITE $SGEN $XNCR”

6. Katy Perry Ditches Alibaba’s Concert After Anti-Trump Tweets

Pop star Katy Perry has pulled out of a star-studded extravaganza put on by China’s largest online retailer.

7. Tesla’s own numbers show Autopilot has higher crash rate than human drivers

A couple of weeks ago, I wrote about Tesla’s claim that its Autopilot driver-assistance software is safer than a human driver. After a fatal Autopilot crash last May, the company said the death was the first in 130 million miles of Autopilot driving—and noted that, “among all…

8. AstraZeneca sees big healthcare changes under Trump

Drugmaker AstraZeneca (AZN.L) expects major U.S. healthcare changes after Donald Trump’s election victory but its chief executive warned on Thursday that pricing pressures in the world’s biggest drugs market would not go away.

9. IEA sees global market awash with oil in 2017 if no OPEC cut

The oil market risks running another surplus in 2017 without an output cut from OPEC, as producers around the globe ramp up supply and demand growth falters, the International Energy Agency said on Thursday.

10. U.S. should have joined China-led infrastructure bank: Trump adviser

A top adviser of U.S. President-elect Donald Trump lashed out at the Obama administration for failing to embrace the China-led Asian Infrastructure Investment Bank (AIIB), suggesting a possible policy shift when Trump takes office in January.

Technology News

Early movers: KSS, MET, COP, PRTY, BBY, CAS, SHAK, TWTR, MYL & more

Check out which companies are making headlines before the bell: Kohl’s – The retailer reported adjusted quarterly profit of 80 cents per share, 10 cents a share above forecasts. Revenue was very slightly above estimates. Same-store sales did fall by 1.7 percent, but that drop was in line with analysts’ projections.

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