PRE-MARKET MOVERS

 

UPGRADES

2. CVX:$CVX upgraded to Overweight at Morgan Stanley – PT raise $130 from $113

 

DOWNGRADES

1. BHI:$BHI downgraded to Outperform at Raymond James

 

EARNINGS

 

Trending Social Alerts

1. PFE:$PFE discontinues development of its PCSK9 inhibitor.
4. BHI:$BHI downgraded to Outperform at Raymond James
5. BABA:surprised Ackman isn’t long $BABA, has accounting irregularities, whistle-blowers and SEC investigations
6. COH:Coach Q1 EPS $0.45 vs $0.45 Est, Revenue $1.04B vs $1.07B Est. $COH
8. SHPG:$SHPG terminates SHP610 after Ph2b study did not meet primary endpoint of slowing cognitive decline in pts with early stage #Sanfilippo A.

 

Trending News Headlines

1. ‘High-up’ Alibaba staffer helping SEC probe into tech giant

A federal probe of Alibaba’s books is far from dead — and it’s getting help from at least one insider. The Securities and Exchange Commission is working with one or more whistleblowers as it invest…

2. Pfizer Discontinues Global Development of Bococizumab, Its Investigational PCSK9 Inhibitor | Pfizer: One of the world’s premier biopharmaceutical companies

Pfizer Inc. announced today the discontinuation of the global clinical development program for bococizumab, its investigational Proprotein Convertase Subtilisin Kexin type 9 inhibitor (PCSK9i). The totality of clinical information now available for bococizumab, taken together with the evolving treatment and market landscape for lipid-lowering agents, indicates that bococizumab is not likely to provide value to patients, physicians, or shareholders. As a result, Pfizer has decided to discontinue the development program, including the two ongoing cardiovascular outcome studies.

3. Pfizer Cuts Outlook, Ends Development of Cholesterol Drug

Pfizer Inc. on Tuesday lowered its earnings outlook for the year and said it was ending the development of a drug in the massive cholesterol-treatment sector.

4. Pfizer profit just misses; company scraps cholesterol drug

Pfizer Inc (PFE.N), the largest U.S. drugmaker, reported a quarterly adjusted profit that just missed analysts’ estimates, and the company shaved 4 cents off its 2016 earnings forecast after scrapping development of a cholesterol-lowering treatment.

5. Gannett ends talks to buy Tronc

This story is developing. Please check back for further updates.

6. Gannett Abandons Its Attempt to Buy Tronc

Newspaper company Gannett has dropped its bid to buy Chicago Tribune publisher Tronc, ending a monthslong pursuit of its rival.

7. Tronc is crashing after Gannett terminates buyout talks

The owner of the USA Today is not buying the owner of the Chicago Tribune and the stocks are crashing.

8. Gannett Abandons Effort to Buy Newspaper Publisher Tronc

Investor expectations will now present tough questions for the former Tribune Publishing, owner of The Los Angeles Times and Chicago Tribune.

9. SAP Ariba Celebrates Two Decades of Procurement Innovation

Twenty years ago, procurement was a manual function driven largely by phone calls, faxes and handshakes. Then along came the Internet. And a company n

10. Drugmaker Sanofi hungry for deals after earnings beat

French drugmaker Sanofi stepped up its overhaul on Friday, putting its European generic drugs business up for sale and saying that a planned 3.5 billion euro ($3.8 billion) share buyback would not suppress its appetite for deals.

11. Press Release | Investor Relations | Ionis Pharmaceuticals

CARLSBAD, Calif. , Nov. 1, 2016 /PRNewswire/ — Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced positive data from a Phase 2 placebo-controlled study evaluating IONIS-FXI Rx in patients with end-stage renal disease (ESRD) on hemodialysis. In this Phase 2 study patients treated with IONIS-FXI Rx achieved statistically significant, dose-dependent reductions in Factor XI activity. There were no clinically meaningful reductions in platelet levels and no treatment-related major or clinically relevant non-major bleeding events.

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